Paracetamol overdose: Two ‘extremely common’ side effects of overdosing paracetamol

PARACETAMOL is a popular painkiller used to treat aches and pain. Although taking the recommended dose is safe for most people, overdosing can cause adverse reactions.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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AbstractOpioid overdose accounted for more than 47,000 deaths in the United States in 2018. The risk of new persistent opioid use following breast cancer surgery is significant, with up to 10% of patients continuing to fill opioid prescriptions one year after surgery. Over prescription of opioids is far too common. A recent study suggested that up to 80% of patients receiving a prescription for opioids post-operatively do not need them (either do not fill the prescription or do not use the medication). In order to address this important issue, The American Society of Breast Surgeons empaneled an inter-disciplinary committe...
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
The opioid crisis has led to increasing numbers of overdose fatalities in teens and young adults. Surgery, as a common cause of acute pain in children, drives much of the opioid prescribing in pediatrics. Therefore, we sought to characterize opioid prescribing practices of pediatric surgeons by surveying members of the American Pediatric Surgery Association (APSA).
Source: Journal of Pediatric Surgery - Category: Surgery Authors: Source Type: research
Chronic opioid therapies (COT) are widely prescribed for the treatment of chronic pain related to palliative care, active cancer, and end-of-life care.43, 189 However, the use of COT to alleviate and manage chronic non-cancer pain (CNCP) remains controversial due to the risk for development of opioid use disorder, overdose, and opioid-related deaths.43 Despite the increased use of opioids to manage a wide range of chronic pain conditions, there is limited data regarding the effectiveness of long-term opioid treatment for CNCP particularly when considering COT as a primary treatment option.
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Review Article Source Type: research
We report a case of unintentional systemic clonidine toxicity in an adult because of a compounded preparation of clonidine applied to a degraded skin barrier. A 35-year-old male suffered a motorcycle accident 48 hours before presentation resulting in an abrasion to his distal left leg. On the day of presentation, he self-treated the wound by repeated application of a family member's pain-relieving cream. Later he was found confused and unable to stand by a family member. The family member recognized the thick visible coat of cream as the likely cause and decontaminated the patient while calling 911. Prehospital vitals were...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
CONCLUSIONS: To our knowledge, this is the first example of a statewide collaboration among diverse health professional education programs to create a single, standard curriculum. This collaborative process and the nonproprietary Arizona Pain and Addiction Curriculum may serve as a useful template for other states to enhance pain and addiction education. PMID: 32962529 [PubMed - as supplied by publisher]
Source: Public Health Reports - Category: International Medicine & Public Health Tags: Public Health Rep Source Type: research
OBJECTIVE: To estimate all-cause and overdose crude mortality rates and standardized mortality ratios among people prescribed opioids for chronic noncancer pain and risk of overdose death in this population relative to people with similar clinical profiles...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
The use of opioid analgesics for pain management has increased dramatically over the past decade, with corresponding increases in negative sequelae including overdose and death. Physicians, policymakers, and researchers are focused on finding ways to decre...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Background Chronic non-cancer pain (CNCP) among patients with substance use disorder (SUD) poses a risk for worse treatment outcomes. Understanding the association of CNCP with SUD is important for informing the need and potential benefits of pain assessm...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
BACKGROUND: Fueled by misinformation, fentanyl panic has harmed public health through complicating overdose rescue while rationalizing hyper-punitive criminal laws, wasteful expenditures, and proposals to curtail vital access to pain pharmacotherapy. To as...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
(University of Pennsylvania School of Nursing) Opioid use disorder and overdose have reached unprecedented levels around the world. In the United States, remediation of pain is one of the most common reasons American adults seek healthcare. Therefore, it is vital that clinicians practicing in diverse roles and settings have a clinical understanding of pain and substance use disorders as well as knowledge about public health and opioid policy interventions.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
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