Determination of the key ccRCC-related molecules from monolayer network to three-layer network

Renal cell carcinoma (RCC) is one of the most common cancers in men and women [1-3]. RCC accounts for 2-3% of all cancers and about 90% of kidney malignancies [4, 5]. Clear cell renal cell carcinoma (ccRCC) is the most ubiquitous subtype in RCC, accounting for 75% of kidney cases [4, 6, 7] and 4% of adult malignancies [8]. Nearly 40% of ccRCC may metastasize to other organs, including lungs, bones, brain and lymph nodes with increasing incidence [8-10]. Therefore, new insights into the pathogenesis of ccRCC will be conducive to diagnosis, treatment and prognosis.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Tags: Original Article Source Type: research