Fight Aging! Newsletter, April 12th 2021

In conclusion, the MR exhibited the protective effects against age-related behavioral disorders, which could be partly explained by activating circulating FGF21 and promoting mitochondrial biogenesis, and consequently suppressing the neuroinflammation and oxidative damages. These results demonstrate that FGF21 can be used as a potential nutritional factor in dietary restriction-based strategies for improving cognition associated with neurodegeneration disorders. Senescent T Cells Cause Changes in Fat Tissue that are Harmful to Long-Term Health https://www.fightaging.org/archives/2021/04/senescent-t-cells-cause-changes-in-fat-tissue-that-are-harmful-to-long-term-health/ There is a much greater awareness in the scientific community of the importance of cellular senescence to aging. Senescent cells are influential in the progression of many facets of aging and age-related disease, and a new industry is working to produce senolytic therapies to clear senescent cells from old tissues. Further, there is funding and interesting for investigations of the many specific ways in which senescent cells cause harm. The open access paper noted here is an example of this sort of research, which the inflammatory signaling of senescent T cells is implicated as a contributing cause of detrimental age-related changes in fat tissue metabolism. It has become evident that adipose tissue plays an endocrine function, not merely an energy reservoir pool, and exerts a fundam...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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ConclusionAcid hydrolysis enhances the skin sensitizing capacity of gluten and drives IgE reactivity to more gluten proteins. This property of acid hydrolyzed gluten may be related to the degree of product deamidation, and could be a strong trigger of wheat allergy in susceptible individuals.
Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Research Article Source Type: research
With the new equipment and facility, New Mexico Cancer Center will ensure the company can offer both types of radiation used for cancer treatment.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Dalton Trans., 2021, Advance Article DOI: 10.1039/D1DT02023D, PaperAhmet T. Bilgi çli, Ceylan Hepokur, Hayriye Genc Bilgicli, Burak Tüzün, Armağan Günsel, Sema Mısır, Mustafa Zengin, M. Nilüfer Yarasir α-substituted phthalocyanines were synthesized due to their promising anticancer compounds. Their aggregation behavior and biological properties were investigated by UV-Vis and fluorescence spectroscopy, as well as molecular docking studies. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
ConclusionsBased on the results of VICTORIA, patients treated with vericiguat had lower rates of heart failure hospitalization and cardiovascular death. The addition of vericiguat to PSoCT was estimated to increase QALYs and to be cost effective at a willingness-to-pay threshold of $100,000 per QALY gained.
Source: PharmacoEconomics - Category: Health Management Source Type: research
The $335.8 million, 182,800-square-foot structure is the first start-to-finish UCSF construction project since the start of the Covid-19 pandemic, with the clinical building opening in 2024.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Do you, as a dentist, have time to travel the world? Did you ever visit China? Africa? Countries in Europe? Etc?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Dental Source Type: forums
The CDC is urging parents and guardians to vaccinate children aged 5 to 11 against COVID-19 once the shot is fully approved.WebMD Health News
Source: Medscape Internal Medicine Headlines - Category: Internal Medicine Tags: Infectious Diseases News Source Type: news
At least 59,000 meatpacking workers caught COVID-19 and 269 workers died last year, which is significantly more than previously thought, according to a new US House report released Wednesday.Associated Press
Source: Medscape FamilyMedicine Headlines - Category: Primary Care Tags: Infectious Diseases News Source Type: news
"WHO Technical Advisory Group for Emergency Use Listing (EUL) is an independent advisory group that provides recommendations to WHO on whether a #COVID19 vaccine can be listed for emergency use under the EUL procedure," the WHO tweeted.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
Local health care executives give their take on the Covid-19 pandemic and challenges they've faced.
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Source Type: news
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