lncRNA C2dat2 facilitates autophagy and apoptosis via the miR-30d-5p/DDIT4/mTOR axis in cerebral ischemia-reperfusion injury

This study first revealed that C2dat2/miR-30d-5p/DDIT4/mTOR forms a novel signaling pathway to facilitate autophagy and apoptosis induced by CIRI, contributing to the better understanding of the mechanisms of CIRI and enriching the ceRNA hypothesis in CIRI.PMID:33833132 | DOI:10.18632/aging.202824

Source: Aging - April 9, 2021 Category: Biomedical Science Authors: Qian Xu Ma Guohui Dandan Li Fanghui Bai Jintao Fang Gui Zhang Yuxin Xing Jiawei Zhou Yugang Guo Yunchao Kan Source Type: research