< em > Clostridioides difficile < /em > toxins enhanced the < em > in vitro < /em > production of CXC chemokine ligand 2 and tumor necrosis factor- α via Toll-like receptors in macrophages

Conclusion. Our results showed that C. difficile toxins, including CDT, enhanced macrophage-mediated CXCL2 and TNF-α production via TLR2 and TLR4, indicating that CDT affects host immune responses.PMID:33830910 | DOI:10.1099/jmm.0.001342

Source: Journal of Medical Microbiology - April 8, 2021 Category: Microbiology Authors: Hiroe Konishi McKee Chiaki Kajiwara Tetsuo Yamaguchi Yoshikazu Ishii Norikazu Shimizu Akira Ohara Kazuhiro Tateda Source Type: research