CD248 enhances tissue factor (TF) procoagulant function, promoting arterial and venous thrombosis in mouse models

CONCLUSION: CD248 is a newly uncovered protein partner and potential therapeutic target in the TF-FVIIa-FX macromolecular complex that modulates coagulation.PMID:33830628 | DOI:10.1111/jth.15338

Source: Thrombosis and Haemostasis - April 8, 2021 Category: Hematology Authors: Piyushkumar R Kapopara Nooshin S Safikhan Jenny L Huang Scott C Meixner Kevin Gonzalez Houra Loghmani Wolfram Ruf Alan E Mast Victor Lei Edward L G Pryzdial Edward M Conway Source Type: research