Multidimensional flow cytometry reveals novel platelet subpopulations in response to prostacyclin

CONCLUSION: The combination of multicolour flow cytometry assays with unbiased computational tools has identified novel platelet subpopulations that suggest differential regulation of platelet functions by PGI2 . Development of this approach with increased surface and intracellular markers will allow the identification of rare platelet subtypes and novel biomarkers.PMID:33834609 | DOI:10.1111/jth.15330

Source: Thrombosis and Haemostasis - April 9, 2021 Category: Hematology Authors: Matthew S Hindle Benjamin Ej Spurgeon Lih T Cheah Beth A Webb Khalid M Naseem Source Type: research