Combination-copanlisib-rituximab-significantly-increases-progression-free-survival-patients-relapsed

Copanlisib is the first and only PI3K inhibitor to demonstrate broad and superior efficacy in combination with rituximab in patients with relapsed indolent non-Hodgkin’s Lymphoma (iNHL) compared to rituximab and placebo / Phase III trial CHRONOS-3 showed the combination of copanlisib and rituximab resulted in a 48% reduction in the risk of disease progression or death in patients with iNHL / The strong reduction in risk of progression or death was observed across all prespecified iNHL subtypes / The adverse event (AE) profile of the copanlisib and rituximab combination was manageable and generally consistent with previous data on copanlisib and rituximab as individual therapies / Bayer is discussing the data from CHRONOS-3 with health authorities worldwide
Source: Bayer Company News - Category: Pharmaceuticals Source Type: news