Influence of postoperative radiotherapy target volumes in unilateral head and neck carcinoma of unknown primary: a multicentric study using propensity score

In about 3 –5% of patients with malignant epithelial tumours, no primary tumour is found despite extensive investigations, leading to the diagnosis of “Cancer of Unknown Primary” (CUP) (1).The most common histology encountered in Head and Neck (HN) CUP (HNCUP) patients is squamous cell carcinoma (SCC) in 66–77%, followed by undifferentiated carcinoma and adenocarcinoma (2). Lymph node metastases are usually located in the upper two-thirds of the neck (levels II-III according to Robbins) mainly deriving from HNSCC (3).

Source: Radiotherapy and Oncology - April 9, 2021 Category: Radiology Authors: Brenet Esteban, Philouze Pierre, Schiffler Camille, Pommier Pascal, Crozes Carole, Benzerdjeb Nazim, Monchet Elodie, Boulagnon-Rombi Camille, Ton Van Jean, Podeur Fabien, Servagi-Vernat St éphanie, Liem Xavier, Merol Jean-Claude, Ceruse Philippe, Serre A Tags: Original Article Source Type: research