Ravidasvir hydrochloride for genotype 1 hepatitis C treatment

Drugs Today (Barc). 2021 Mar;57(3):199-208. doi: 10.1358/dot.2021.57.3.3251711.ABSTRACTEffective oral combination regimens have been approved for treatment of hepatitis C virus (HCV) infection and demonstrated high cure rates in different HCV genotypes. These direct-acting agents target a variety of HCV proteins, including HCV-NS5A (nonstructural protein 5A). Ravidasvir hydrochloride, a potent pan-genotypic HCV-NS5A inhibitor approved in Egypt for treatment of HCV genotype 4 (G4), demonstrated impressive efficacy, safety profiles and a high barrier to resistance in multiple clinical trials when used as a key component in combination with other direct-acting agents in treating patients with HCV-G1.PMID:33729217 | DOI:10.1358/dot.2021.57.3.3251711
Source: Drugs of Today - Category: Drugs & Pharmacology Authors: Source Type: research