Standard radiotherapy for patients with nasopharyngeal carcinoma results in progressive tract-specific brain white matter alterations: A one-year follow-up via diffusion tensor imaging

Nasopharyngeal carcinoma (NPC) is one of the most common malignant head and neck cancers in Southern China and Southeast Asia [1]. Radiation therapy (RT), with or without adjuvant chemotherapy, is the mainstay treatment modality for patients with NPC due to its radiosensitivity [2]. However, RT also exhibits several caveats, as increasing evidence has shown that RT in NPC patients is correlated with cognitive impairment, which significantly influences the quality of life (QOL) in affected patients [3,4].

Source: Radiotherapy and Oncology - April 8, 2021 Category: Radiology Authors: Yingwei Qiu, Zheng Guo, Xiaoshan Lin, Jing Li, Zhipeng Li, Lujun Han, Yadi Yang, Xiaofei Lv Tags: Original Article Source Type: research