BCR/ABL1-positive B-lymphoblastic Lymphoma Successfully Treated with Dasatinib-combined Chemotherapy
Intern Med. 2021 Apr 5. doi: 10.2169/internalmedicine.7066-21. Online ahead of print.ABSTRACTWe herein report a rare case of BCR-ABL1-positive B-lymphoblastic lymphoma (B-LBL). An 18-year-old woman had a history of persistent left-sided chest pain. Positron emission tomography showed increased metabolic activity in the fifth rib, duodenum, and pancreas. The pathological findings of the pancreas, duodenum, and bone marrow confirmed the diagnosis of B-LBL. Polymerase chain reaction of duodenum and bone marrow also revealed a minor BCR-ABL1 fusion gene. She was diagnosed with BCR-ABL1-positive B-LBL and administered dasatinib and prednisolone. She achieved complete remission two weeks after the initiation of the treatment. She received stem cell transplantation after consolidation chemotherapy and sustained complete remission.PMID:33814500 | DOI:10.2169/internalmedicine.7066-21
Source: Internal Medicine - Category: Internal Medicine Authors: Chika Yamada Yoshimitsu Shimomura Kimimori Kamijyo Madoka Kanda-Kato Satoshi Yoshioka Daisuke Yamashita Takayuki Ishikawa Source Type: research
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