An international study reveals how the 'guardian' of the genome works

(Centro Nacional de Investigaciones Oncol ó gicas (CNIO)) * Teams from the CNIO, the Leiden University Medical Center and the Netherlands Cancer Institute use electron cryo-electron microscopy to explain how the MutS protein, considered the 'guardian' of the genome, manages to repair the errors that can occur in DNA during cell division* An in-depth understanding of this process is essential to understand how mutations occur that can lead to the development of certain types of tumour, such as Lynch syndrome and endometrial cancer
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news