The effect of patient positioning (prone or supine) on the dose received by small bowel in pelvic radiotherapy in rectal cancer patients

CONCLUSION: Supine position could be accepted for the patients undergoing preoperative rectal cancer chemo-radiation.PMID:33812778 | DOI:10.1016/j.canrad.2020.04.013
Source: Cancer Radiotherapie - Category: Cancer & Oncology Authors: Source Type: research

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ConclusionPET/MR provides a more precise assessment of the local extent of rectal cancers in evaluating cancer length, N status, and external sphincter involvement. PET/MR offers the opportunity to improve clinical decision-making, especially when evaluating low rectal tumors with possible external sphincter involvement.
Source: European Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research
ConclusionsWe present the world's first TaTME simulator and believe that it will play an important role for the safe spread of TaTME surgery.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
ConclusionsSacrococcygeal curvature and distance as well as tumour distance from the anal margin were associated with specimen quality in anterior resection. Coccygectomy was not performed as completely as surgeons thought. Surgeons should include sacrococcygeal bony anatomy in rectal cancer surgical planning to potentially improve outcomes in both anterior resection and eLAPE approaches.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
CONCLUSION: MR-guided radiotherapy using daily full online recontouring and replanning on a 1.5T MR-linac for rectal cancer is feasible and currently takes about 48 minutes per fraction. PMID: 32976875 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
CONCLUSIONS: CT scan plays an important role in the preoperative staging of rectal cancer, which is helpful for judging the tumor site and infiltration, and highly accurate for T1-T2 lesions, but has limitations for lymph node metastasis. CT scan also has great value for distant metastasis, and contributes to the development of clinical therapeutic regimens for patients with rectal cancer in different stages. CT stage has an influence on the prognosis and patient survival. PMID: 32862586 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
ConclusionsThe model elaborated showed good performance, even when data from patients scanned on 1.5  T and 3 T were merged. This shows that magnetic field intensity variability can be overcome by means of selecting appropriate image features.
Source: La Radiologia Medica - Category: Radiology Source Type: research
Authors: Noh GT, Chung SS, Kim KH, Lee RA Abstract Purpose: Narrow pelvis has been considered an adverse factor for postoperative and oncologic outcomes after rectal cancer surgery. The aim of this study was to investigate the validity of using only axial CT scan images to calculate the pelvic cross-sectional area for the prediction of adverse outcomes after rectal cancer surgery. Methods: The medical records of patients who underwent rectal cancer surgery were reviewed and analyzed retrospectively. Axial images of CT scan were used to measure the pelvic cross-sectional area. Pelvic surgical site infection (SSI...
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
At the moment, international guidelines for rectal cancer suggest to consider 18F-FDG PET/CT scan in a few conditions: (1) at disease presentation in case of suspected or proven metastatic synchronous adenocarcinoma with potentially curable M1 disease; (2) in the recurrence workup for serial carcinoembryonic antigen level elevation; (3) in the recurrence workup with metachronous metastases documented by CT, MRI, or biopsy; (4) in case of strong contraindication to IV contrast agent administration; and (5) to evaluate an equivocal finding on a contrast-enhanced CT or MRI. PET/CT is not indicated in the follow-up or surveill...
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Opinion Paper/Commentary Source Type: research
Conclusions: Radiomic texture and shape descriptors of the rectal wall from post-treatment T2w MRIs may be associated with low and high pathologic tumor stage after neoadjuvant chemoradiation therapy and generalized across variations between scanners and institutions.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
The objectives of this study were to assess survival outcomes in patients with and without mrEMVI and to compare the prognostic value of mrEMVI with other rectal cancer features.MethodsIn a Dutch high volume rectal cancer center cohort of sixty-seven locally advanced rectal cancer patients, an independent radiologist reviewed all primary staging MRI scans. The presence of mrEMVI was correlated to tumor specific and survival outcomes.Results20/67 patients had mrEMVI positive rectal cancer. 55% (11/20) developed metachronous metastases, compared with 23% (11/47) in the mrEMVI negative group (OR 4.0,p = 0.01). Overall surviva...
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
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