Effect of Hesperidin against Induced Colon Cancer in Rats: Impact of Smad4 and Activin A Signaling Pathway

CONCLUSION: This study demonstrated the chemopreventive effect of Hsd against CRC by modulating Smad4 and activin A signaling in vivo. Further studies are needed to demonstrate its clinical value and explore its possible role in advanced malignancy.PMID:33818196 | DOI:10.1080/01635581.2021.1907424
Source: Nutrition and Cancer - Category: Cancer & Oncology Authors: Source Type: research