Semantic enrichment of clinical models towards semantic interoperability. The heart failure summary use case

Conclusion We show how an ontology-based representation of a clinical summary, guided by semantic patterns, allows homogeneous querying of heterogeneous information structures. Whether there are a finite number of top-level patterns is an open question.
Source: Journal of the American Medical Informatics Association - Category: Information Technology Authors: Tags: Research and Applications Source Type: research

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Publication date: Available online 17 January 2020Source: PhytomedicineAuthor(s): Rui Guo, Ningning Liu, Hao Liu, Junhua Zhang, Han Zhang, Yingchao Wang, Mirko Baruscotti, Lu Zhao, Yi WangAbstractBackground: Cardiac hypertrophy is a prominent feature of heart remodeling, which may eventually lead to heart failure. Tongmaiyangxin (TMYX) pills is a clinically used botanical drug for treating multiple cardiovascular diseases including chronic heart failure. The aim of the current study was to identify the bioactive compounds in Tongmaiyangxin pills that attenuate cardiomyocytes hypertrophy, and to investigate the underlying m...
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Most people know about the damaging effects that binge drinking can bring to someone’s life. Loss of enjoyment of life, losing family relationships, financial and career struggles, homelessness, and legal consequences are just the tip of the iceberg. However, it can be more difficult to realize the long-term effect of binge drinking on the body, because you cannot always see it. Frequent binge drinking poses many dangerous health risks, and many of them can lead to death. Facts on Long-Term Effect of Binge Drinking on the Body For men, binge drinking is defined as consuming five or more drinks within about two hour...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism alcohol abuse alcohol dependence alcohol treatment alcohol treatment center binge binge drinking Source Type: blogs
BioCardia, a Silicon Valley firm, won FDA clearance for its Morph DNA catheter, a device developed to help with delivery of the company’s CardiAMP cell therapy into the heart. CardiAMP involves depositing a patient’s own bone marrow cells...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiac Surgery Cardiology Source Type: blogs
Conclusion It was safety to discontinued oral antiplatelet agents before operation, with no MACE and death in perioperative period. 
 DOI: 10.3779/j.issn.1009-3419.2020.01.06
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
Authors: Du Z, Xu W, Chen X, Xu D, Li Y, Zhang H, Gao L PMID: 31937077 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Authors: Saritas T, Floege J Abstract Patients with chronic kidney disease (CKD) are at increased risk for kidney failure, cardiovascular disease (CVD), and death. In fact, the likelihood of dying from CVD is markedly higher than that for reaching end-stage renal disease. Evidence-based management of comorbidities such as CVD remains challenging in patients with advanced CKD, as they were usually excluded from randomized controlled trials. This review focuses on the epidemiology, risk factors, and clinical manifestations of CVD in patients with advanced CKD. Specific topics of interest include diagnostic and therap...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
I'm still a medical student (IMG), but I can easily tell how good a doctor is in non-surgical specialties. I can simply look up what they are saying and see if it makes sense. When one of my teachers said "End diastolic volume decreases in systolic heart failure" and stuck with that assertion after I questioned it, I knew that I should stick to a textbook for instruction. I'm rewatching a cell phone video of a foot amputation we got to see and I'm wondering how "correct" the surgical... How can you tell if a surgeon is good?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Medical Students - MD Source Type: forums
Heart failure is a leading cause of morbidity and mortality globally. The natural history of heart failure with reduced ejection fraction (HFrEF) has been altered with the development of multiple therapeutic agents targeting maladaptive biologic pathways, including angiotensin-converting enzyme inhibitors (ACEi)/angiotensin receptor blockers (ARBs), β-blockers, and mineralocorticoid antagonists (MRAs). While mechanistic studies overlapped, the landmark trials and their publications that led to the acceptance of these therapies as standards of care generally occurred sequentially.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Commentary Source Type: research
AbstractHyperbaric oxygenation therapy is successfully implemented for the treatment of several disorders. Data on the effect of hyperbaric oxygenation on echocardiographic parameters in asymptomatic patients is limited. The current study sought to evaluate the effect of hyperbaric oxygenation therapy on echocardiographic parameters in asymptomatic patients. Thirty-one consecutive patients underwent a 60-sessions course of hyperbaric oxygenation therapy in an attempt to improve cognitive impairment. In all subjects, echocardiography examination was performed before and after a course of hyperbaric oxygenation therapy. Conv...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
Methamphetamine is a central nervous system stimulant initially synthesized from ephedrine in 1893 by the Japanese chemist Nagai Nagayoshi. It was utilized in World War II by Allied and Axis forces for their effects on performance enhancement.1 Because of rising abuse, methamphetamines became a schedule II controlled substance in the United States in 1971.2 Over the past 50 years, there has been a gradual increase in the incidence of methamphetamine abuse followed by a recent rapid rise. Although methamphetamine abuse was dramatized in the popular TV series Breaking Bad, the epidemic has largely been overshadowed by overdo...
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Tags: Brief Report Source Type: research
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