Activation of TRPV1 Channel by dietary capsaicin improves visceral fat remodeling through Connexin43-mediated Ca 2+ Influx

Conclusion: This study demonstrated that capsaicin activation of TRPV1-evoked increased Ca2+ influx in Cx43-mediated adipocyte-to-adipocyte communication promotes lipolysis in both vitro and vivo. TRPV1 activation by dietary capsaicin improves visceral fat remodeling through the up-regulation of Cx43.

http://www.cardiab.com/content/14/1/22

Source: Cardiovascular Diabetology - February 13, 2015 Category: Cardiology Authors: Jian ChenLi LiYingsha LiXia LiangQianqian SunHao YuJian ZhongYinxing NiJing ChenZhigang ZhaoPeng GaoBin WangDaoyan LiuZhiming ZhuZhencheng Yan Source Type: research