Higher systemic oxidatively generated DNA and RNA damage in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives

CONCLUSION: Overall, the findings of higher oxidative stress in patients with newly diagnosed BD and their UR suggest that systemic nucleoside damage by oxidative stress is present prior to onset and in the early stages of BD thereby potentially representing trait markers of BD.PMID:33798615 | DOI:10.1016/j.freeradbiomed.2021.03.022

Source: Free Radical Biology and Medicine - April 2, 2021 Category: Biology Authors: Klara Coello Helena Lykke B øgh Sharleny Stanislaus Hanne Lie Kj ærstad Sigurd A Melbye Kimie Stefanie Ormstrup Sletved Henrik Enghusen Poulsen Maj Vinberg Lars Vedel Kessing Source Type: research