Immunogenicity and safety of sabin-strain based inactivated poliovirus vaccine replacing salk-strain based inactivated poliovirus vaccine: An innovative application of different strain-IPVs replacement

CONCLUSIONS: The Salk-Sabin-Sabin IPV immunization schedule is not inferior to the Salk-Salk-Salk IPV schedule in terms of both immunogenicity and safety. Clinical trial number: NCT04051736.PMID:33810904 | DOI:10.1016/j.vaccine.2021.02.073

Source: Vaccine - April 3, 2021 Category: Allergy & Immunology Authors: Haiping Chen Zhigang Gao Shuang Bai Xiaoqin Liu Shasha Han Yanhui Xiao Fang Liu Yinghong Yu Hongmei Sun Xiaoming Yang Source Type: research