Teduglutide for pediatric short bowel syndrome patients

This article reviews and educates the reader on this novel pharmacologic therapy and its use in pediatrics.Areas covered: This article reviews the pharmacology, safety, efficacy, and tolerability of GLP-2 analogue teduglutide in pediatric patients greater than 1 year of age. We review all current studies and discuss teduglutide's place in pediatric SBS therapy.Expert opinion: Teduglutide marks the first successful pharmacological intervention that augments the natural process of adaptation safely and effectively in SBS pediatric patients. More studies and further development are needed to optimize its potential in other pediatric patients.PMID:33798402 | DOI:10.1080/17474124.2021.1913052
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research