Production and activity of matrix metalloproteinases during liver fibrosis progression of chronic hepatitis C patients

CONCLUSION: High concentrations of inactive MMPs were present in the serum of CHC patients, reflecting the impossibility to restrain liver fibrosis progression. MMPs could be good diagnostic candidates and therapeutic targets for improving novel strategies to reverse liver fibrosis in CHC.PMID:33708351 | PMC:PMC7934014 | DOI:10.4254/wjh.v13.i2.218

Source: World Journal of Hepatology - March 12, 2021 Category: Gastroenterology Authors: Moises Martinez-Castillo Abigail Hernandez-Barragan Ivonne Flores-Vasconcelos Marina Galicia-Moreno Dorothy Rosique-Oramas Jose Luis Perez-Hernandez Fatima Higuera-De la Tijera Eduardo E Montalvo-Jave Aldo Torre-Delgadillo Paula Cordero-Perez Linda Mu ño Source Type: research