Targeting SLC3A2 subunit of system X < sub > C < /sub > < sup > - < /sup > is essential for m < sup > 6 < /sup > A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma

In conclusion, YTHDC2 is believed to be a powerful endogenous ferroptosis inducer and targeting SLC3A2 subunit of system XC- is essential for this process. Increasing YTHDC2 is an alternative ferroptosis-based therapy to treat LUAD.PMID:33785413 | DOI:10.1016/j.freeradbiomed.2021.03.023
Source: Free Radical Biology and Medicine - Category: Biology Authors: Source Type: research