Targeting SLC3A2 subunit of system X < sub > C < /sub > < sup > - < /sup > is essential for m < sup > 6 < /sup > A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma
In conclusion, YTHDC2 is believed to be a powerful endogenous ferroptosis inducer and targeting SLC3A2 subunit of system XC- is essential for this process. Increasing YTHDC2 is an alternative ferroptosis-based therapy to treat LUAD.PMID:33785413 | DOI:10.1016/j.freeradbiomed.2021.03.023
Source: Free Radical Biology and Medicine - Category: Biology Authors: Lifang Ma Xiao Zhang Keke Yu Xin Xu Tianxiang Chen Yi Shi Yikun Wang Shiyu Qiu Susu Guo Jiangtao Cui Yayou Miao Xiaoting Tian Lutao Du Yongchun Yu Jinjing Xia Jiayi Wang Source Type: research