NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers

ConclusionMHC-I could be identified as a target for anti-tumor and allogeneic immunity. Consequently, NLRC5 could be a promising target for immunotherapy and vaccines to protect devils from transmissible cancers and inform development of transplant and cancer therapies for humans.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research