Studies of the Role of Basophils in Aspirin Exacerbated Respiratory Disease Pathogenesis

Capsule Summary: Increased basophil numbers and extent of ongoing degranulation in nasal polyps of patients with AERD compared to CRSwNP may contribute to the exaggerated disease pathogenesis and severity unique to AERD.

Source: Journal of Allergy and Clinical Immunology - April 2, 2021 Category: Allergy & Immunology Authors: Whitney W. Stevens, Anna G. Staudacher, Kathryn E. Hulse, Julie A. Poposki, Atsushi Kato, Roderick G. Carter, Lydia A. Suh, James E. Norton, Julia H. Huang, Anju T. Peters, Leslie C. Grammer, David B. Conley, Stephanie Shintani-Smith, Bruce K. Tan, Kevin Source Type: research