What Is Endometriosis and How Is It Treated?
Title: What Is Endometriosis and How Is It Treated?Category: Health NewsCreated: 3/30/2021 12:00:00 AMLast Editorial Review: 3/30/2021 12:00:00 AM
Over the last years, increasing evidence has focused on crucial pathogenetic role of PRL on malignant, premalignant and benign uterine diseases. Studies in animals and humans have documented that PRL receptors (PRL-Rs) are widely expressed on uterine cells and that PRL is directly synthesized by the endometrium under the stimulatory action of progesterone. Uterine PRL secretion is finely modulated by autocrine/paracrine mechanisms which do not depend on the same control factors implied in the regulation of PRL secretion from pituitary. On the other hand, PRL is synthesized also in the myometrium and directly promotes uteri...
Conclusion(s)Although generalized linear models may allow identification of endometriosis, we did not obtain perfect classification with the selected gene candidates.
To study reproductive outcomes, and pregnancy and delivery complications after conservative or operative treatment of rectovaginal endometriosis during long-term follow-up.
Authors: Dana PM, Taghavipour M, Mirzaei H, Yousefi B, Moazzami B, Chaichian S, Asemi Z Abstract Endometriosis is a pathology form of endometrium that behaves in a similar way to malignancies, such as invasion and resistance to apoptosis. Circular RNAs (CircRNAs) are a class of noncoding RNAs that have several biological functions including, miRNA sponging, sequestering of proteins, enhancing parental gene expression and translation resulting in polypeptides. In this review, we highlighted the roles of circRNAs as potential diagnostic and therapeutic biomarkers in endometriosis. Moreover, we summarized the roles of...
Endometriosis is encountered in approximately 40% of infertile women. The mechanisms by which endometriosis causes infertility are multiple with none truly prevailing in the clinical cases commonly encountered. In addition, infertility caused by endometriosis is not absolute, but relative, as severe cases of endometriosis have even been reported in women who had conceived spontaneously. In one review article (1), we sorted all endometriosis-related factors of infertility according to the location where these are expressed, as follows: the pelvic cavity, the ovaries, and the uterus itself.
AbstractPurposeEndometriosis (EM) is a common gynecological disease affecting 10 –15% of women of reproductive age. However, molecular mechanisms and pathogenesis are still not completely understood. Furthermore, due to the absence of a reliable clinical biomarker, the only viable method for the often-delayed definitive diagnosis is laparoscopic surgery. Our objective was to a nalyze molecular differences of selected endometrial proteins and genes of women suffering from different stages of EM compared with healthy women to evaluate potential clinical biomarkers.MethodsWe analyzed eutopic endometrial tissue samples f...
Publication date: Available online 4 October 2020Source: Gynecologic Oncology ReportsAuthor(s): Kieran Seay, Tracey Akanbi, Bethany Bustamante, Shweta Chaudhary, Gary L. Goldberg
To study whether markers of prenatal exposure to reproductive hormones are related to Mayer-Rokitansky-K üster-Hauser (MRKH) syndrome, polycystic ovary syndrome (PCOS), and endometriosis.
To evaluate the ultrasonographic presence of different forms of endometriosis and the associated clinical symptoms in adolescent women.