Pemafibrate, A Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator, Reduces Plasma Eicosanoid Levels and Ameliorates Endothelial Dysfunction in Diabetic Mice

CONCLUSION: Pemafibrate diminished the levels of vasoconstrictive eicosanoids and free fatty acids accompanied by a reduction of triglyceride. These effects may be associated with the improvement of endothelial function by pemafibrate in diabetic mice.PMID:33775978 | DOI:10.5551/jat.61101

Source: Journal of Atherosclerosis and Thrombosis - March 29, 2021 Category: Cardiology Authors: Kumiko Suto Daiju Fukuda Masakazu Shinohara Byambasuren Ganbaatar Shusuke Yagi Kenya Kusunose Hirotsugu Yamada Takeshi Soeki Ken-Ichi Hirata Masataka Sata Source Type: research