Effect of serum urate lowering with allopurinol on blood pressure in young adults: A randomized, controlled, crossover trial

ConclusionsUrate ‐lowering therapy with allopurinol in young adults did not lower SBP or hs‐CRP when compared with placebo, despite improvements in FMD. These findings do not support urate‐lowering as a treatment for hypertension in young adults.

Source: Arthritis and Rheumatology - March 29, 2021 Category: Rheumatology Authors: Angelo L Gaffo, David A. Calhoun, Elizabeth J. Rahn, Suzanne Oparil, Peng Li, Tanja Dudenbostel, Daniel I. Feig, David T Redden, Paul Muntner, Phillip J Foster, Stephanie R Biggers ‐Clark, Amy Mudano, Sebastian E Sattui, Michael B Saddekni, Tags: FULL LENGTH Source Type: research