Autoantibodies Against the Purkinje Cell Protein RGS8 in Paraneoplastic Cerebellar Syndrome

Conclusion Our results indicate that autoantibodies against the intracellular Purkinje cell protein RGS8 represent new markers for paraneoplastic cerebellar syndrome associated with lymphoma. Classification of Evidence This study provided Class IV evidence that autoantibodies against the intracellular Purkinje cell protein RGS8 are associated with paraneoplastic cerebellar syndrome in lymphoma.

http://nn.neurology.org/cgi/content/short/8/3/e987?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - March 29, 2021 Category: Neurology Authors: Miske, R., Scharf, M., Stark, P., Dietzel, H., Bien, C. I., Borchers, C., Kermer, P., Ott, A., Denno, Y., Rochow, N., Borowski, K., Finke, C., Teegen, B., Probst, C., Komorowski, L. Tags: Autoimmune diseases, Gait disorders/ataxia, Paraneoplastic syndrome, Class IV Article Source Type: research