Markers of disease activity in COPD: an 8-year mortality study in the ECLIPSE cohort

Conclusions
In COPD, 1- and 3-year changes in exacerbation frequency, systemic inflammation, BODE and SGRQ scores and FEV1 decline are independent markers of disease activity associated with 8-year all-cause mortality. These disease activity markers are generally independent and not predictable from baseline measurements.

Source: European Respiratory Journal - March 25, 2021 Category: Respiratory Medicine Authors: Celli, B., Locantore, N., Yates, J. C., Bakke, P., Calverley, P. M. A., Crim, C., Coxson, H. O., Lomas, D. A., MacNee, W., Miller, B. E., Mullerova, H., Rennard, S. I., Silverman, E. K., Wouters, E., Tal-Singer, R., Agusti, A., Vestbo, J., for the Evaluat Tags: COPD and smoking Original Articles: COPD Source Type: research