Extended gene panel testing in lobular breast cancer

Conclusion: The overall PGV detection rate was 11.59%, with similar rates ofBRCA1/2 (7.28%) PGVs as for other actionable PGVs (7.46%), indicating a benefit for extended panel genetic testing in LBC. We also report a previously unrecognised association of pathogenic variants inATM with LBC.
Source: Familial Cancer - Category: Cancer & Oncology Source Type: research