Pharmacogenomics and functional imaging to predict irinotecan pharmacokinetics and pharmacodynamics: the predict IR study

ConclusionsExploratory associations were observed between Irinotecan PK/PD with hepatic functional imaging and extensive pharmacogenomics. Further work is required to confirm and validate these findings in a larger cohort of patients.Australian New Zealand Clinical Trials Registry (ANZCTR) NumberACTRN12610000897066, Date registered: 21/10/2010.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research