Inhibition of fibroblast growth factor-inducible 14 attenuates experimental tubulointerstitial fibrosis and profibrotic factor expression of proximal tubular epithelial cells

ConclusionsIn conclusion, TWEAK/Fn14 signals contributed to tubulointerstitial fibrosis by acting on proximal tubular epithelial cells.Fn14 inhibition might be a therapeutic strategy for protecting against renal interstitial fibrosis.
Source: Inflammation Research - Category: Research Source Type: research