Blistering severe cutaneous adverse reactions in children: Proposal for pediatric-focused clinical criteria

Br J Dermatol. 2021 Mar 17. doi: 10.1111/bjd.20063. Online ahead of print.ABSTRACTSevere cutaneous adverse reactions (SCARs) are challenging to diagnose and manage in children for two main reasons: 1) The literature on SCARs in children is sparse and extrapolated from adult data, 2) Many paediatric blistering SCAR cases are qualified as 'atypical' or 'incomplete' erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) because certain clinical features make them not fit into this adult classification. Our panel proposes paediatric-focused clinical criteria for blistering SCARs in children to improve early diagnosis and facilitate acute management.PMID:33730370 | DOI:10.1111/bjd.20063

Source: The British Journal of Dermatology - March 17, 2021 Category: Dermatology Authors: M L Ramien A Bahubeshi I Lara-Corrales E Pope M L Levy A J Nopper N H Shear L Eichenfield Source Type: research