OSCC cell-secreted exosomal CMTM6 induced M2-like macrophages polarization via ERK1/2 signaling pathway

ConclusionOSCC cell-secreted exosomalCMTM6 induces M2-like macrophages polarization to promote malignant progression via ERK1/2 signaling pathway, revealing a novel crosstalk between cancer cells and immune cells in OSCC microenvironment.

Source: Cancer Immunology, Immunotherapy - March 20, 2021 Category: Cancer & Oncology Source Type: research