Routine KIT p.D816V screening identifies clonal mast cell disease in Hymenoptera allergic patients regularly missed using baseline tryptase levels alone

Capsule summaryPresence of the KIT p.D816V is most commonly associated with normal BST, while H αT is the most common cause of elevated BST, among individuals with severe HVA and should be considered clinically to risk-stratify patients with venom allergy.

Source: Journal of Allergy and Clinical Immunology - March 19, 2021 Category: Allergy & Immunology Authors: Julij Šelb, Matija Rijavec, Renato Eržen, Mihaela Zidarn, Peter Kopač, Matevž Škerget, Nissera Bajrović, Ajda Demšar Luzar, Young Hwan Park, Yihui Liu, Vladka Čurin Šerbec, Samo Zver, Mitja Košnik, Jonathan J. Lyons, Peter Korošec Source Type: research