What You Should Know Before You Schedule Your Next Doctor Appointment

Before we were able to Google our every itch and twinge and ache, we had very different relationships with our doctors. “In the early years of my career, information was something the doctor had and the patient didn’t,” Dr. Michael L. LeFevre, a professor and physician at the University of Missouri, tells The Huffington Post. Today, he says, patients bring their information to him for his input. “They want my opinion about how good the information is and what it means and how to interpret it for them in their lives.” Of course, the Internet is rife with misinformation, and sometimes a well-meaning patient will ask for a bout of tests that are completely unnecessary. But at the end of the day, LeFevre thinks this has still resulted in a more empowered patient, one who can arm herself with the tools to help get herself the best care. That is, assuming patients still go to the doctor's office at all. Recently, bioethicist and physician (and no stranger to controversial proclamations) Dr. Ezekiel Emanuel declared the annual physical "worthless." Using slightly milder language, other medical authorities have also suggested that getting a yearly screening might not be the best use of time or money. Much of the conversation has to do with the types of screening tests that are done at the doctor's office. LeFevre is also chair of the U.S. Preventive Services Task Force, an independent panel of experts that provides screening and preventio...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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In this study, five population databases plus the Catalog of Somatic Mutations in Cancer was employed to demonstrate the impact of changing the PF cut-off on assignment of variants as germline versus somatic. The 1% to 2% PF cut-offs widely used in bioinformatic pipelines result in high sensitivity for classification of somatic variants, but unnecessarily reduced sensitivity for germline variants. Using optimized PF cut-offs, the source of variants in TCGA data could be predicted with>95% accuracy. Further exploration of four TCGA cancer datasets indicated that the optimal cut-off is influenced by both cancer type and t...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
Publication date: Available online 25 June 2019Source: The Journal of Molecular DiagnosticsAuthor(s): Paolo A. Ascierto, Carlo Bifulco, Giuseppe Palmieri, Solange Peters, Nikoletta SidiropoulosAn enduring goal of personalized medicine in cancer is the ability to identify patients who are likely to respond to specific therapies. Our growing understanding of the biology and molecular signatures of individual tumor types has facilitated the identification of predictive biomarkers and has led to an increasing number of diagnostic tests to be performed, often as serial and distinct assays on limited tumor specimens. The biomark...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
Objective The aim of this study was to use an electronic tablet–based education module to increase patient knowledge about human papillomavirus (HPV). Methods Patients presenting to an academic colposcopy clinic were first queried as to whether they had been infected with HPV. A quality improvement project was then conducted using a 4-question pretest assessing baseline knowledge about HPV and cancer, followed by a tablet-based education module and a 5-question posttest. Results Between June 2017 and January 2018, 119 patients participated in the tablet education. At their initial visit, only 50 (42.0%) of pa...
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research
Conclusions Both methods of sampling were found to be acceptable to women. Self-sampling is cost-effective and could increase the screening coverage among underscreened populations. However, more information about the quality, reliability, and accuracy of self-sampling is needed to increase women's confidence about using to this method.
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research
Conclusions Self-collected anorectal swab samples showed lower sensitivity but moderate to high specificity for detection of high-risk and vaccine-preventable HPV types compared with clinician-collected swab samples. Self-collection instructional details and the thoroughness of clinician collection of samples may have impacted sensitivity and specificity, suggesting a need to optimize and standardize instructions.
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Original Research Article: Perianal and Anal Source Type: research
No abstract available
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Forum Source Type: research
Nashville-based E+CancerCare (stylized e+CancerCare) has been sold to a Newport Beach, California, company, according to a news release. Integrated Oncology Network LLC, a portfolio company of Silver Oak Services Partners LLC, announced Wednesday it has bought E+CancerCare. Terms of the deal were not disclosed. Founded in 2002, E+CancerCare operates 21 outpatient cancer treatment centers in 21 states, according to the release. The company’s centers provide diagnostic testing, radiation oncology…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
We report the cases of two patients, one 26 years-old male, and the other 43 years-old female, who had a history of high blood pressure and hypokalemia. The male also presented progressive tetraparesis six months before diagnosis. The female patient was diagnosed with systemic lupus erythematosus and Sjögren's syndrome. After investigation, using ultrasonography and abdominal computed tomography, both patients presented hypodense and solid nodular lesions in the adrenal gland, compatible with adenoma. The surgical team opted for a hybrid minimally invasive approach. Providing a better visualization of the surgical fie...
Source: Current Medicine Research and Practice - Category: General Medicine Source Type: research
ConclusionIt seems that human breast cancer and BLV infection in cattle could be associated using nested PCR technique.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionsMore research is necessary to understand why cervical cancer screenings are not associated with receipt of an AFV.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
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