Exploratory study of the effectiveness of nebulised saline in children with neurodisability

Respiratory morbidity is an important cause of hospitalisation and death in children with neurodisability [1]. Such children may have impaired respiratory function and inefficient cough due to weak bulbar and respiratory musculature, increased upper airway collapsibility and low lung compliance [2, 3]. Nebulised hypertonic saline (HS), usually 3% or 7%, is used to manage and prevent respiratory exacerbations in conditions such as cystic fibrosis (CF) and non-CF bronchiectasis. In patients with CF and non-CF bronchiectasis, nebulised HS has been associated with better airway clearance and lung function [4–8].

Source: European Respiratory Journal - March 18, 2021 Category: Respiratory Medicine Authors: Galaz Souza, N., Bush, A., Tan, H.-L. Tags: Original Articles: Research letters Source Type: research