Incomplete Administration of Intravenous Vancomycin Prophylaxis is Common and Associated With Increased Infectious Complications Following Primary Total Hip and Knee Arthroplasty

Vancomycin is often used as antimicrobial prophylaxis in patients undergoing total hip or knee arthroplasty. Vancomycin requires longer infusion times to avoid associated side effects. We hypothesized that Vancomycin infusion is often started too late, and that delayed infusion may predispose patients to increased rates of surgical site infections and prosthetic joint infections.

Source: The Journal of Arthroplasty - March 18, 2021 Category: Orthopaedics Authors: Oren I. Feder, David Yeroushalmi, Charles C. Lin, Matthew S. Galetta, Moretza Meftah, Claudette M. Lajam, James D. Slover, Ran Schwarzkopf, Joseph A. Bosco, William B. Macaulay Source Type: research