Pharmacological ablation of astrocytes reduces A β degradation and synaptic connectivity in an ex vivo model of Alzheimer’s disease

Astrocytes provide a vital support to neurons in normal and pathological conditions. In Alzheimer ’s disease (AD) brains, reactive astrocytes have been found surrounding amyloid plaques, forming an astrocytic s...

Source: Journal of Neuroinflammation - March 17, 2021 Category: Neurology Authors: Nicola Davis, Bibiana C. Mota, Larissa Stead, Emily O. C. Palmer, Laura Lombardero, Rafael Rodr íguez-Puertas, Vincenzo de Paola, Samuel J. Barnes and Magdalena Sastre Tags: Research Source Type: research