Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer's disease

DISCUSSION: Our study in post-mortem human brains and transgenic AD mice provided neuropathological and functional evidence that cerebellar dysfunction may occur at the early stage of AD and likely independent of Aβ plaque.PMID:33688799 | DOI:10.1080/01616412.2021.1893566

Source: Neurological Research - March 10, 2021 Category: Neurology Authors: Kiran Chaudhari Linshu Wang Jonas Kruse Ali Winters Nathalie Sumien Ritu Shetty Jude Prah Ran Liu Jiong Shi Michael Forster Shao-Hua Yang Source Type: research