H2FPEF score

H2FPEF score H2FPEF score is a simple scoring system using clinical characteristics and echocardiography for differentiation of heart failure with preserved ejection fraction (HFpEF) from noncardiac causes of dyspnea [1]. H2FPEF score was developed by Reddy YNV et al using a derivation cohort of 414 consecutive patients comprising of 267 cases with HFpEF and 147 controls. The test cohort included 100 consecutive patients of which 61 had HFpEF. It was a retrospective study in consecutive patients with unexplained dyspnea referred for invasive hemodynamic exercise testing. The variables used and their weighted scores were as follows: H2 Heavy: Body mass index > 30 Kg/m2: 2 points      Hypertensive: 2 or more antihypertensive medications: 1 point F Atrial Fibrillation: Paroxysmal or Persistent: 3 points P Pulmonary hypertension: Pulmonary artery systolic pressure estimated by Doppler echocardiography > 35 mm Hg: 1 point E Elder: Age > 60 years: 1 point F Filling Pressure: Doppler Echocardiographic E/e’ > 9: 1 point Total score possible would range from 0 – 9 points. The odds of HFpEF doubled for each 1 unit increase in H2FPEF score.  The authors suggested that low H2FPEF scores of 0 or 1 can be used to effectively rule out the disease, while scores of 6-9 can be used to make a diagnosis of HFpEF with good confidence. Intermediate scores of 2-5 would call for additional testing [1]. Suzuki S et al did an external validation o...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Cardiology Source Type: blogs