We Can Treat Alzheimer's Disease Successfully in Mice but Not in Men: Failure in Translation? A Perspective.

Conclusion: The value of animal models depends mainly on the careful experimentation and correct interpretation of results. Appropriate planning of experiments will help to increase the predictive value in drug development programs, though this may also increase negative findings. However, the early failure may enable a faster focus on more promising strategies. © 2014 S. Karger AG, Basel. PMID: 24401335 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24401335?dopt=Abstract

Source: Neuro-Degenerative Diseases - January 7, 2014 Category: Neurology Authors: Windisch M Tags: Neurodegener Dis Source Type: research