Preoperative weight loss in women with obesity in gynaecologic oncology: A retrospective study

SummaryTo retrospectively review the efficacy of short term supervised medical weight loss for women with obesity, body mass index (BMI ≥40 kg/m2) in gynaecologic oncology, and the associated perioperative and pathologic outcomes. A retrospective study of a dedicated preoperative weight loss clinic for gynaecologic oncology patients from March to December 2019. Statistical analysis was performed with McNemar's test for correlated proportions, Pearson's correlation tests for continuous variables, and pairedt‐tests to compare means. Generalized estimating equations (GEE) were used to determine the factors associated with weight loss over time. AP‐value of<.05 was used for statistical significance. Review of cases up ‐graded after surgery was performed by a gynaecologic pathologist. There were a total of 49 women included in the study. The most common referral reason was endometrioid carcinoma or hyperplasia of the endometrium (77.6%). Mean initial weight was 130.2 kg, and corresponding mean BMI 48.1 kg/m2. Patients attended on average nine preoperative weight loss visits. A significant difference between initial weight and weight at surgery was demonstrated, from 129.6 to 118.0 kg (8.4% weight loss) (P  < .0001). This difference persisted to their post ‐surgical visit, with an additional mean loss of 1.89 kg (9.4% weight loss) (P  = .044). The majority (92.1%) of patients with endometrial pathology had surgical management, and of these 85.7% were minimal...
Source: Clinical Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Original Research Article Source Type: research