Cyclic guanosine monophosphate and 10-year change in left ventricular mass: the Multi-Ethnic Study of Atherosclerosis (MESA)

Conclusion: In conclusion, in a community-based cohort, higher cGMP levels were associated with increase in LVM over 10 years independent of CVD risk factors and NT-proBNP in men, perhaps reflecting compensatory changes. Further studies are needed to understand mechanistic roles of cGMP in LV remodelling and associated sex differences.PMID:33715578 | DOI:10.1080/1354750X.2021.1893811

Source: Biomarkers - March 15, 2021 Category: Research Authors: Vinita Subramanya Di Zhao Pamela Ouyang Wendy Ying Dhananjay Vaidya Chiadi E Ndumele Joao A Lima Eliseo Guallar Ron C Hoogeveen Sanjiv J Shah Susan R Heckbert David A Kass Wendy S Post Erin D Michos Source Type: research