Anti-GM2 antibody positive Guillain-Barr é syndrome presenting with ataxia in a pediatric patient: An atypical manifestation

Guillain-Barr é syndrome (GBS) is the most prevalent cause of acquired paralytic neuropathy in children, however, ataxia as the initial presenting sign in children is very rare. Antiganglioside antibodies are presumed to have an important role in the pathophysiology and some phenotypic correlations have been rep orted. Anti-GM2 antibody, unlike other antibodies, is far less detected in GBS. Here, we report a 7.5-year-old female, initially presenting with ataxia, an atypical presenting symptom in a child, is promptly diagnosed and treated successfully as GBS.
Source: Brain and Development - Category: Neurology Authors: Tags: Case Report Source Type: research