Do combined assays of serum AFP, AFP-L3, DCP, GP73, and DKK-1 efficiently improve the clinical values of biomarkers in decision-making for hepatocellular carcinoma? A meta-analysis

CONCLUSION: : The combined assay of AFP and GP73 conferred the best outcome among all panels. The triple combined panel of AFP, AFP-L3, and DCP showed higher diagnostic potential than individual random double combinations of the three biomarkers. Multiple-biomarker combined assays will be clinically important for decision-making processes for HCC.PMID:33691550 | DOI:10.1080/17474124.2021.1900731

Source: Expert Review of Gastroenterology and Hepatology - March 11, 2021 Category: Gastroenterology Authors: Yong-Sheng Fang Qiang Wu Hong-Chuan Zhao Yuan Zhou Lei Ye Sheng-Sheng Liu Xiao-Xue Li Wei-Dong Du Source Type: research