A new highly divergent copiparvovirus in sheep

AbstractThe subfamilyParvovirinae within the familyParvoviridae consists of viruses that can infect a wide range of vertebrate hosts and cause effects ranging from severe disease to asymptomatic infection. In the present study, high-throughput sequencing (HTS) was utilized to analyze samples obtained from an abortion outbreak in a sheep flock to identify a putative viral etiology. A highly divergent nearly complete parvovirid genome sequence, approximately 4.9 kb in length, was determined. The nonstructural protein (NS1) amino acid (aa) sequence of this virus shared less than 30% identity with those of other copiparvoviruses and less than 22% identity with those of members of other genera in the subfamilyParvovirinae. Phylogenetically, this virus, which we have provisionally named"sheep copiparvovirus 1", formed a cluster with copiparvovirus sequences and should be classified as a member of a new species in the genusCopiparvovirus.

Source: Archives of Virology - March 10, 2021 Category: Virology Source Type: research