The investigation of genetic and clinical features in patients with hereditary spastic paraplegia in central ‐Southern China

ConclusionsOur findings strongly support variable phenotype ofB4GALNT1‐related SPG26 and also expand the clinical and mutation spectrum of HSP caused by mutations inSPAST,SPG11, andB4GALNT1. These results will help to improve the efficiency of early diagnosis in patients clinically suspected of HSP.

Source: Molecular Genetics & Genomic Medicine - February 27, 2021 Category: Genetics & Stem Cells Authors: Chen Wang, Yun ‐Jian Zhang, Ci‐Hao Xu, Li De, Zhi‐Jun Liu, Yan Wu Tags: ORIGINAL ARTICLE Source Type: research