Invited commentary to: ADAMTS13 deficiency is associated with abnormal distribution of von Willebrand factor multimers in patients with COVID-19 by Tiffany Pascreau et al. Letter to the Editors-in-Chief, Thrombosis Research
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is the cause of a world-wide pandemic that has caused more than 2.5 million deaths worldwide as of mid February 2021 since its onset in December 2019. Severely affected patients suffer from pneumonia, necessitating invasive ventilation and several groups showed a high incidence and prevalence of venous and arterial thromboembolic events of large vessels and also microvascular thrombosis of the pulmonary circulation [1 –3]. Hemostatic laboratory parameters at admission of COVID-19 patients, especially strongly elevated D-dimer levels, were predictive of mortality [4].
Source: Thrombosis Research - Category: Hematology Authors: Bernhard L ämmle, Heidi Rossmann Tags: Letter to the Editors-in-Chief Source Type: research
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