Profiling phenome-wide associations: a population-based observational study.
CONCLUSIONS: The correlation analysis of pairwise disease association patterns across different age and gender groups led to outcomes that were broadly predicted before the analysis, thus confirming the validity of the information contained in the presented database. More diverse individual disease-specific analyses would lead to a better understanding of phenome-wide associations and empower physicians to provide personalized care in terms of predicting, preventing, or initiating an early management of concomitant diseases. PMID: 25656518 [PubMed - as supplied by publisher]
Publication date: Available online 20 January 2020Source: Trends in Food Science &TechnologyAuthor(s): I.P. Shanura Fernando, BoMi Ryu, Ginnae Ahn, In-Kyu Yeo, You-Jin JeonAbstractBackgroundMetabolic syndrome (MS) defines a group of severe comorbidities, including insulin resistance, abnormal fat accumulation, and high blood pressure that lead to obesity, diabetes, and heart diseases. MS has received a growing concern due to its rising prevalence in many countries. The consumption of high-calorie food, sedentary lifestyle habits, genetic factors, and stress conditions aggravate risk factors for developing metabolic syn...
Publication date: Available online 20 January 2020Source: Pathology - Research and PracticeAuthor(s): Neha Bakshi, Natasha Gulati, Archana Rastogi, Abhijit Chougule, Chhagan Bihari, Ankur JindalaAbstractIntroductionNodular regenerative hyperplasia (NRH) is a rare hepatic vascular disorder which is often associated with wide variety of systemic diseases. Intrahepatic microvascular injury and subsequent altered perfusion state leads to development of non-cirrhotic portal hypertension in many of these patients. Diagnosis of NRH often remains unsuspected clinically and liver biopsy is essential for the diagnosis and exclusion ...
Publication date: Available online 21 January 2020Source: Pregnancy HypertensionAuthor(s): Christina Antza, Chrisa Dimou, Ioannis Doundoulakis, Evangelos Akrivos, Stella Stabouli, Anna Bettina Haidich, Dimitrios G. Goulis, Vasilios kotsisAbstractThe present systematic review and meta-analysis investigated the effects of hydralazine compared with other antihypertensive drugs in maternal, perinatal and neonatal outcomes of pregnant women with hypertensive disorders. Twenty studies with 1283 participants were included. Of them, 626 received hydralazine and 657 other antihypertensive treatments, such as labetalol, nifedipine, ...
ConclusionA combination of depressive symptoms and CRP was implicated in the onset of CHD, stroke, diabetes/high blood glucose, and pulmonary disease up to 12 years later, reflecting the role of psychobiological processes across multiple disease states.
[Vanguard] In recent times, the number of people coming down with kidney disease has been on the increase and many reasons have been adduced to explain the rise in number of cases. Chief among the reasons are the rise in cases of diabetes and high blood pressure; which experts say, increase the risk of chronic kidney disease. However, one disease which experts say could lead to kidney failure, respiratory disease, meningitis, liver failure and even death if left untreated, is little known leptospirosis, considered th
HIGH blood pressure can lead to long-term and potentially fatal health complications if left untreated, but the condition can be easily reversed if measures are taken to lead a healthier lifestyle. Even small tweaks can go a long way to lowering blood pressure, and evidence suggests sprinkling three ingredients on your porridge is a great way to lower your blood pressure at the beginning of the day.
CONCLUSIONS: These findings suggest that there are significant differences in personality traits between hypertensive patients with and without vascular and cardiac damage. PMID: 31955182 [PubMed - in process]
(World Scientific) A search using medical data bases reveals that hundreds of meta-analysis papers conducted with tens of millions of people worldwide have confirmed clinically the efficacies of 30 antioxidant-rich foods to prevent or treat chronic diseases, including hypertension, diabetes, cardiovascular disease, cognitive impairment, chronic kidney disease, cancer, and more. Professor Monte Lai, former professor of biophysics at the Medical College of Wisconsin talks about this and more in his new book 'The Food Cure.'